TY - CHAP A1 - Tadesse Sheleme ED1 - Juber Akhtar ED2 - Usama Ahmad ED3 - Badruddeen ED4 - Mohammad Irfan Khan Y1 - 2021-12-15 PY - 2021 T1 - Clinical Pharmacokinetics of Metformin N2 - Type 2 diabetes (T2D), also known as non-insulin-dependent diabetes mellitus (NIDDM), is a condition in which cells fail to respond to insulin properly. As the disease progresses, the body does not produce enough insulin. There are several classes of anti-diabetic medications available, including the oral agent metformin. This medication is recommended as first-line treatment for T2D, except for those patients with severe kidney or liver problems. This book discusses the molecular mechanism, pharmacokinetics, and uses of metformin, as well as presents information on adverse drug reactions, drug interactions, and the potential use of metformin in tuberculosis. BT - Metformin SP - Ch. 3 UR - https://doi.org/10.5772/intechopen.99343 DO - 10.5772/intechopen.99343 SN - 978-1-83969-606-0 PB - IntechOpen CY - Rijeka Y2 - 2022-05-27 ER -