TY - CHAP A1 - Nagindra Prashad ED1 - Pasquale Cianci ED2 - Enrico Restini ED3 - Amit Agrawal Y1 - 2021-08-18 PY - 2021 T1 - Targeting MYC and HDAC8 with a Combination of siRNAs Inhibits Neuroblastoma Cells Proliferation In Vitro and In Vivo Xenograft Tumor Growth N2 - Pheochromocytoma, paraganglioma and neuroblastoma are the most common neural crest-derived tumors in adults and children, respectively. These neoplasms are associated with significant morbidity and mortality. Some international studies currently underway are researching and evaluating the presence of any similarities and differences between these tumors. Hopefully, future results will reveal several potential novel genes and pathways that might have major roles in the pathogenesis and progression of these neoplasms. This book discusses epidemiology, genetics, and treatment of these malignancies. BT - Pheochromocytoma, Paraganglioma and Neuroblastoma SP - Ch. 7 UR - https://doi.org/10.5772/intechopen.96021 DO - 10.5772/intechopen.96021 SN - 978-1-83968-948-2 PB - IntechOpen CY - Rijeka Y2 - 2021-10-25 ER -