TY - CHAP A1 - Manish Shandilya A2 - Shrutika Sharma A3 - Prabhu Prasad Das A4 - Sonika Charak ED1 - Hilal Arnouk ED2 - Bassam Abdul Rasool Hassan Y1 - 2021-07-21 PY - 2021 T1 - Molecular-Level Understanding of the Anticancer Action Mechanism of Anthracyclines N2 - Recent advances in precision medicine and immuno-oncology have led to highly specific and efficacious cancer therapies such as monoclonal antibodies and immune checkpoint inhibitors (ICIs). This book provides an up-to-date overview of advances in the field of immuno-oncology. Chapters cover such topics as ICIs and how they mount a robust immune response against cancer cells as well as the response of ICIs to treatment predictive biomarkers and their potential immune-related adverse events (irAEs). Additionally, the book includes a comprehensive review of the powerful FDA-approved therapeutic agent doxorubicin, highlighting the molecular mechanisms behind doxorubicin’s drug resistance and critical side effects. BT - Advances in Precision Medicine Oncology SP - Ch. 9 UR - https://doi.org/10.5772/intechopen.94180 DO - 10.5772/intechopen.94180 SN - 978-1-83968-868-3 PB - IntechOpen CY - Rijeka Y2 - 2022-01-22 ER -