TY - CHAP A1 - Benjamin Wadowski A2 - David T. Severson A3 - Raphael Bueno A4 - Assunta De Rienzo ED1 - Sonia MaciĆ” Y1 - 2020-11-11 PY - 2020 T1 - Genetic Alterations of Malignant Pleural Mesothelima N2 - Mesothelioma is an aggressive cancer with very poor survival and lack of treatment options. This book, written by a diverse panel of experts, presents a description of the most relevant topics on epidemiology, diagnosis, biomarkers, and treatment updates, including interesting discussion on molecular mechanisms, prognostic features, and novel therapies that are either approved or under clinical development for this challenging disease. It also discusses and explains genetic biomarkers, as there may be a role for some nuclear regulatory genes and proteins in development of mesothelioma, although targeted therapies so far have had limited impact. BT - Mesothelioma SP - Ch. 7 UR - https://doi.org/10.5772/intechopen.93756 DO - 10.5772/intechopen.93756 SN - 978-1-83968-155-4 PB - IntechOpen CY - Rijeka Y2 - 2022-05-24 ER -