TY - CHAP A1 - Ana Sofia Martins Serras A2 - Madalena Zincke dos Reis Fernandes Cipriano A3 - Pedro Miguel da Graça Silva A4 - Joana Paiva Gomes Miranda ED1 - Diana Kitala ED2 - Ana Colette Maurício Y1 - 2021-04-14 PY - 2021 T1 - Challenges for Deriving Hepatocyte-Like Cells from Umbilical Cord Mesenchymal Stem Cells for In Vitro Toxicology Applications N2 - In the 1950s, Nobel Prize winner Dr. E. Donnall Thomas was the first to successfully transplant hematopoietic stem cells. Since then, studies on stem cells have evolved and expanded worldwide. There are more than 650,000 scientific publications on stem cells and more than 8000 stem cell clinical trials. This book summarizes types of stem cells, key studies, ongoing trials, and future perspectives. It also includes ethical, formal, and legal aspects to give the reader a comprehensive view of the field. BT - Novel Perspectives of Stem Cell Manufacturing and Therapies SP - Ch. 8 UR - https://doi.org/10.5772/intechopen.91794 DO - 10.5772/intechopen.91794 SN - 978-1-83962-513-8 PB - IntechOpen CY - Rijeka Y2 - 2021-06-21 ER -