TY - CHAP A1 - Thuluz Meza Menchaca A2 - Claudia Juárez-Portilla A3 - Rossana C. Zepeda ED1 - Vishwanath Gaitonde ED2 - Partha Karmakar ED3 - Ashit Trivedi Y1 - 2020-03-11 PY - 2020 T1 - Past, Present, and Future of Molecular Docking N2 - The process of drug discovery and development is a complex multistage logistics project spanned over 10-15 years with an average budget exceeding 1 billion USD. Starting with target identification and synthesizing anywhere between 10k to 15k synthetic compounds to potentially obtain the final drug that reaches the market involves a complicated maze with multiple inter- and intra-operative fields. Topics described in this book emphasize the progresses in computational applications, pharmacokinetics advances, and molecular modeling developments. In addition the book also contains special topics describing target deorphaning in Mycobacterium tuberculosis, therapy treatment of some rare diseases, and developments in the pediatric drug discovery process. BT - Drug Discovery and Development SP - Ch. 2 UR - https://doi.org/10.5772/intechopen.90921 DO - 10.5772/intechopen.90921 SN - 978-1-78923-976-8 PB - IntechOpen CY - Rijeka Y2 - 2021-05-13 ER -