TY - CHAP A1 - Ali Gamal Al-kaf ED1 - Ali Gamal Al-kaf Y1 - 2020-05-06 PY - 2020 T1 - Introductory Chapter: The Newest Research in Quinazolinone and Quinazoline Derivatives N2 - One of the problems with modern public health is target searching for new highly effective medicinal preparations. Among those medicinal preparations are the natural and synthetic origins of quinazolinone-4 derivatives. Quinazolinone derivatives are reported to be physiologically and pharmacologically active. They also exhibit a wide range of activities such as anticonvulsant, antiinflammatory, antifungal, antimalarial, and sedative properties. Some of these compounds are identified as drugs used as diuretics, vasodilators, and antihypertensive agents. Moreover, sulfonamide derivatives have been widely used as bacteriostatic agents. Prompted by the above-mentioned facts and in conjunction with our ongoing program on the utility of readily obtainable starting material for the synthesis of heterocyclic systems of biological interest, we have decided to synthesize a series of quinazolinone derivatives having sulfonamide moiety with a potentially wide spectrum of biological responses. BT - Quinazolinone and Quinazoline Derivatives SP - Ch. 1 UR - https://doi.org/10.5772/intechopen.88913 DO - 10.5772/intechopen.88913 SN - 978-1-83880-140-3 PB - IntechOpen CY - Rijeka Y2 - 2021-09-28 ER -