TY - CHAP A1 - Janka Vašková A2 - Ladislav Vaško ED1 - Janka Vašková ED2 - Ladislav Vaško Y1 - 2019-03-13 PY - 2019 T1 - Introductory Chapter: Unregulated Mitochondrial Production of Reactive Oxygen Species in Testing the Biological Activity of Compounds N2 - The area covered by this book undoubtedly includes a multidisciplinary approach. It combines and uses the wide range of methods and knowledge from a variety of disciplines in chemistry, pharmacology, and biology to synthesize new or extracted natural substances and their characterization, in terms of bioefficiency in different systems, pharmacokinetics, and pharmacodynamics. Importance is placed on revealing the interactions and effects on organisms. The process is long term, ranging from synthesis to potential testing of substances in animal studies, followed by monitoring effects on patients. The purpose is to define molecular targets of the highest efficacy of the prepared drugs, minimizing the undesirable effects. The content of this book is conceived with these intentions. BT - Medicinal Chemistry SP - Ch. 1 UR - https://doi.org/10.5772/intechopen.82514 DO - 10.5772/intechopen.82514 SN - 978-1-78985-174-8 PB - IntechOpen CY - Rijeka Y2 - 2021-11-29 ER -