TY - CHAP A1 - Hai-Long Wu A2 - Xiao-Dong Sun A3 - Huan Fang A4 - Ru-Qing Yu ED1 - Vu Dang Hoang Y1 - 2019-03-20 PY - 2019 T1 - High-Order Calibration and Data Analysis in Chromatography N2 - Chromatography approaches are widely used in various life science applications. Since its invention by the Russian botanist Mikhail S. Tsvet in 1901, chromatography has increasingly developed into an invaluable laboratory tool for the separation and identification of chemical components. It outperforms older techniques (such as crystallization, solvent extraction, and distillation) by offering unequaled resolving power and the possibility of lowering detection limits to below nanogram levels. To further improve chromatographic methods, however, the use of chemometrics is advisable as an economical alternative to resolve any problematic situations in analysis. This book intends to provide the readers with an up-to-date application of chemometrics and data analysis to different types of chromatographic methods. BT - Chemometrics and Data Analysis in Chromatography SP - Ch. 5 UR - https://doi.org/10.5772/intechopen.78624 DO - 10.5772/intechopen.78624 SN - 978-1-78923-836-5 PB - IntechOpen CY - Rijeka Y2 - 2021-11-28 ER -