TY - CHAP A1 - Lancelot Jamie Millar ED1 - Kusal K. Das ED2 - Mallanagouda Shivanagouda Biradar Y1 - 2018-12-12 PY - 2018 T1 - Perinatal and Neonatal Hypoxia Ischaemia: The Unique Challenges of Treating the Infant Brain N2 - The molecular deprivation of oxygen is manifested by hypoxia, a deficiency of oxygen and anoxia, or the absence of oxygen supply to the tissues. This book entitled Hypoxia and Anoxia will cover a broad range of understanding on hypoxia and anoxia from molecular mechanisms to pathophysiology. Hypoxia and anoxia stimulate multiple systems through specific cell signal transduction pathways and regulate several transcriptional factors like HIF-1, REST to encode genes for VEGF, Epo, etc. This book will also highlight different types of hypoxia and anoxia along with their impact on apoptosis, cardiovascular pathophysiology, and glucose regulatory mechanisms. This book will be a ready reckoner to give a deep understanding of the oxygen-sensing environment in vivo for researchers, academicians, and clinicians throughout the world. BT - Hypoxia and Anoxia SP - Ch. 5 UR - https://doi.org/10.5772/intechopen.79674 DO - 10.5772/intechopen.79674 SN - 978-1-78984-829-8 PB - IntechOpen CY - Rijeka Y2 - 2022-01-22 ER -