TY - CHAP A1 - Alexandra Bastian A2 - Luciana Nichita A3 - Sabina Zurac ED1 - Francesco Travascio Y1 - 2017-12-20 PY - 2017 T1 - Matrix Metalloproteinases in Melanoma with and without Regression N2 - Matrix metalloproteinases (MMPs) are a family of proteolytic zinc-containing enzymes involved in physiological as well as in pathological processes in the human organism. MMPs play a key role in the remodeling of the extracellular matrix. Such a process may occur because of tissue homeostasis, morphogenesis, and tissue repair. However, remodeling could also be a part of many pathological states such as arthritis, cardiovascular diseases, neurodegenerative diseases, or impaired development in congenital anomalies. This book overviews the role of MMPs in different pathologies affecting the human body. BT - The Role of Matrix Metalloproteinase in Human Body Pathologies SP - Ch. 7 UR - https://doi.org/10.5772/intechopen.72931 DO - 10.5772/intechopen.72931 SN - 978-953-51-3718-4 PB - IntechOpen CY - Rijeka Y2 - 2019-11-15 ER -