TY - CHAP A1 - Han Wei A2 - Lakshmi Prabhu A3 - Antja-Voy Hartley A4 - Matthew Martin A5 - Emily Sun A6 - Guanglong Jiang A7 - Yunlong Liu A8 - Tao Lu ED1 - Fumiaki Uchiumi Y1 - 2018-02-21 PY - 2018 T1 - Methylation of NF-κB and its Role in Gene Regulation N2 - "Central dogma" was presented by Dr. Francis Crick 60 years ago. The information of nucleotide sequences on DNAs is transcribed into RNAs by RNA polymerases. We learned the mechanisms of how transcription determines function of proteins and behaviour of cells and even how it brings appearances of organisms. This book is intended for scientists and medical researchers especially who are interested in the relationships between transcription and human diseases. This volume consists of an introductory chapter and 14 chapters, divided into 4 parts. Each chapter is written by experts in the basic scientific field. A collection of articles presented by active and laboratory-based investigators provides recent advances and progresses in the field of transcriptional regulation in mammalian cells. BT - Gene Expression and Regulation in Mammalian Cells SP - Ch. 14 UR - https://doi.org/10.5772/intechopen.72552 DO - 10.5772/intechopen.72552 SN - 978-953-51-3856-3 PB - IntechOpen CY - Rijeka Y2 - 2022-05-21 ER -