TY - CHAP A1 - Sabina Oreska A2 - Michal Tomcik ED1 - Mislav Radic Y1 - 2017-10-04 PY - 2017 T1 - Atherosclerosis and Cardiovascular Risk in Systemic Sclerosis N2 - Systemic sclerosis is a rare autoimmune disease characterized by immunological alterations, small vessel vasculopathy, and skin and other organ fibrosis. Despite progress in the knowledge of pathogenic steps and therapeutic options, when compared with other rheumatic conditions, it shows the lowest life expectancy rate. Early diagnosis is important as early treatment could lead to better outcomes. Great progress has been made in the treatment of specific symptoms; however, there are still no disease-modifying drugs that are able to control the overall disease activity satisfactorily. This book covers the latest knowledge in systemic sclerosis from pathophysiology to clinical presentation and management. Hopefully, this book will be a useful resource to students, residents, rheumatologists, dermatologist, and anyone interested in this fascinating disease. BT - Systemic Sclerosis SP - Ch. 2 UR - https://doi.org/10.5772/67495 DO - 10.5772/67495 SN - 978-953-51-3548-7 PB - IntechOpen CY - Rijeka Y2 - 2019-12-09 ER -