TY - CHAP A1 - Marinela Bostan A2 - Mirela Mihaila A3 - Camelia Hotnog A4 - Coralia Bleotu A5 - Gabriela Anton A6 - Viviana Roman A7 - Lorelei Irina Brasoveanu ED1 - Luis Rodrigo Y1 - 2016-09-07 PY - 2016 T1 - Modulation of Apoptosis in Colon Cancer Cells by Bioactive Compounds N2 - Colorectal cancer (CRC) is a major health problem because it represents around 10% of all cancers and achieves a worldwide estimate of 1.4 million newly diagnosed cases annually, resulting in approximately 700,000 deaths. Approximately 19-31% of patients present liver metastases. At diagnosis, a further 23-38% will develop extra-hepatic disease. Over the past decade, the widespread use of modern chemotherapeutic and biological agents, combined with laparoscopic surgical techniques, has improved the prognosis of metastatic CRC. A better understanding of the biology of the tumor, along with high efficiency of diagnostic and therapeutic methods, as well as the spread of screening programs, will improve the survival of the CRC patients in the near future. BT - Colorectal Cancer SP - Ch. 3 UR - https://doi.org/10.5772/63382 DO - 10.5772/63382 SN - 978-953-51-2545-7 PB - IntechOpen CY - Rijeka Y2 - 2021-07-26 ER -