TY - CHAP A1 - Massimo Cocchi A2 - Lucio Tonello A3 - Fabio Gabrielli ED1 - Yong-Ku Kim Y1 - 2015-06-11 PY - 2015 T1 - The Molecular and Quantum Approach to Psychopathology and Consciousness — From Theory to Experimental Practice N2 - Major depressive disorder (MDD) is a complex and heterogeneous disorder, phenotypically and biologically. MDD may be caused by complex interaction between genes and environment in susceptible individuals. Thus, a combination of certain genetic polymorphism, environmental stress, and personal susceptibility ultimately may induce MDD. Gene-environment interactions in the pathophysiology of MDD lead to advancement in personalized medicine by means of genotyping for inter-individual variability in drug action and metabolism. Gene-environment interactions may explain why some subjects become depressed while others remain unaffected. The aim of this book is to describe current knowledge of MDD from the point of view of neurobiology, molecular genetics and cognition. The authors address a deep understanding of cognitive and neurobiological mechanisms involved in MDD. BT - Major Depressive Disorder SP - Ch. 3 UR - https://doi.org/10.5772/59392 DO - 10.5772/59392 SN - PB - IntechOpen CY - Rijeka Y2 - 2019-12-08 ER -