TY - CHAP A1 - Nicholas Kang A2 - Warren Smith ED1 - Steven W. Kerrigan Y1 - 2013-06-27 PY - 2013 T1 - Surgical Management of Infective Endocarditis N2 - Endocarditis is an inflammation of the lining of the heart and valves. It can be due to a non-infectious cause but when the inflammation is associated with an infection, usually bacterial, it is known as infective endocarditis. It is typically characterized by the development of a large septic thrombus on one of the cardiac valves. As this thrombus grows, it can lead to valve failure or may fragment forming a septic embolus that is associated with high mortality if the target of the embolus is the brain, heart or lung. This book reviews multi-organ complications associated with Infective endocarditis including significant recent advances in molecular mechanisms underlying thrombus formation on the cardiac valve, anti-microbial treatment and surgery. BT - Recent Advances in Infective Endocarditis SP - Ch. 5 UR - https://doi.org/10.5772/56761 DO - 10.5772/56761 SN - PB - IntechOpen CY - Rijeka Y2 - 2022-05-26 ER -