TY - CHAP A1 - Verdon Taylor ED1 - Luca Bonfanti Y1 - 2013-04-24 PY - 2013 T1 - Neural Stem Cell Heterogeneity N2 - Twenty years after the discovery of neural stem cells, the question whether the central nervous system can be considered among regenerative tissues is still open. On one side, deep characterization of neural stem and progenitor cells, their niches, and their progeny in brain neurogenic sites overtly showed that new neurons can be generated in the brain of adult mammals, including humans. On the other side, many problems arise when stem cells encounter the mature brain parenchyma, still hampering the development of efficacious therapeutic approaches with endogenous or exogenously-delivered neural stem cells. This book tries to make the point on these extremely promising, yet unresolved, issues. BT - Neural Stem Cells SP - Ch. 2 UR - https://doi.org/10.5772/55676 DO - 10.5772/55676 SN - PB - IntechOpen CY - Rijeka Y2 - 2021-11-29 ER -