TY - CHAP A1 - Mirela Petrulea A2 - Adriana Muresan A3 - Ileana Duncea ED1 - Mohammed Amr El-Missiry Y1 - 2012-10-03 PY - 2012 T1 - Oxidative Stress and Antioxidant Status in Hypo- and Hyperthyroidism N2 - Free radicals are constantly formed in living cells and removed by antioxidant defenses. Antioxidant enzymes are the main line of defense against free radicals in animal and plant cells. Uncontrolled generation ROS are involved in a number of human disease states, including diabetes and cancer due to disturbance in cellular and molecular processes including cell growth, differentiation and proliferation. When cells are exposed to oxidative stress a defense system endorses the expression and regulation of number of antioxidant enzymes as a defense mechanism to protect them from the damage induced by free radicals. Based on this fact, the book "Antioxidant Enzymes" was designed to overview the importance of the antioxidant enzymes in human and plant cells against toxic free radicals, their relationship with several pathophysiologic processes and their possible therapeutic application. BT - Antioxidant Enzyme SP - Ch. 8 UR - https://doi.org/10.5772/51018 DO - 10.5772/51018 SN - PB - IntechOpen CY - Rijeka Y2 - 2019-11-12 ER -