TY - CHAP A1 - Ambarish Nag A2 - Michael I. Monine A3 - Byron Goldstein A4 - James R. Faeder A5 - Michael L. Blinov ED1 - Gabriela Da Silva Xavier Y1 - 2012-06-05 PY - 2012 T1 - Mathematical Modeling of Syk Activation in Allergen-Stimulated Mast Cells and Basophils N2 - Proteins are the work horses of the cell. As regulators of protein function, protein kinases are involved in the control of cellular functions via intricate signalling pathways, allowing for fine tuning of physiological functions. This book is a collaborative effort, with contribution from experts in their respective fields, reflecting the spirit of collaboration - across disciplines and borders - that exists in modern science. Here, we review the existing literature and, on occasions, provide novel data on the function of protein kinases in various systems. We also discuss the implications of these findings in the context of disease, treatment, and drug development. BT - Advances in Protein Kinases SP - Ch. 11 UR - https://doi.org/10.5772/38618 DO - 10.5772/38618 SN - PB - IntechOpen CY - Rijeka Y2 - 2019-11-19 ER -