TY - CHAP A1 - Daisuke Fukushi A2 - Seiji Mizuno A3 - Kenichiro Yamada A4 - Reiko Kimura A5 - Yasukazu Yamada A6 - Toshiyuki Kumagai A7 - Nobuaki Wakamatsu ED1 - Zuzana Storchova Y1 - 2012-05-16 PY - 2012 T1 - Aneuploidy and Intellectual Disability N2 - Aneuploidy means any karyotype that is not euploid, anything that stands outside the norm. Two particular characteristics make the research of aneuploidy challenging. First, it is often hard to distinguish what is a cause and what is a consequence. Secondly, aneuploidy is often associated with a persistent defect in maintenance of genome stability. Thus, working with aneuploid, unstable cells means analyzing an ever changing creature and capturing the features that persist. In the book Aneuploidy in Health and Disease we summarize the recent advances in understanding the causes and consequences of aneuploidy and its link to human pathologies. BT - Aneuploidy in Health and Disease SP - Ch. 6 UR - https://doi.org/10.5772/35879 DO - 10.5772/35879 SN - PB - IntechOpen CY - Rijeka Y2 - 2021-02-27 ER -