TY - CHAP A1 - Jnanankur Bag A2 - Quishan Wang A3 - Rumpa Biswas Bhattacharjee ED1 - Madhuri Hegde and Arunkanth Ankala Y1 - 2012-05-09 PY - 2012 T1 - Nuclear Poly (A)-Binding Protein and Oculopharyngeal Muscular Dystrophy N2 - With more than 30 different types and subtypes known and many more yet to be classified and characterized, muscular dystrophy is a highly heterogeneous group of inherited neuromuscular disorders. This book provides a comprehensive overview of the various types of muscular dystrophies, genes associated with each subtype, disease diagnosis, management as well as available treatment options. Though each different type and subtype of muscular dystrophy is associated with a different causative gene, the majority of them have overlapping clinical presentations, making molecular diagnosis inevitable for both disease diagnosis as well as patient management. This book discusses the currently available diagnostic approaches that have revolutionized clinical research. Pathophysiology of the different muscular dystrophies, multifaceted functions of the involved genes as well as efforts towards diagnosis and effective patient management, are also discussed. Adding value to the book are the included reports on ongoing studies that show a promise for future therapeutic strategies. BT - Muscular Dystrophy SP - Ch. 2 UR - https://doi.org/10.5772/31110 DO - 10.5772/31110 SN - PB - IntechOpen CY - Rijeka Y2 - 2021-06-15 ER -