TY - CHAP A1 - Ricardo García-Muñoz A2 - Judit Anton-Remirez A3 - Jesus Feliu A4 - María Pilar Rabasa A5 - Carlos Panizo A6 - Luis Llorente ED1 - Jagat R. Kanwar Y1 - 2012-05-09 PY - 2012 T1 - Is Chronic Lymphocytic Leukemia a Mistake of Tolerance Mechanisms? N2 - Immunology is the branch of biomedical sciences to study of the immune system physiology both in healthy and diseased states. Some aspects of autoimmunity draws our attention to the fact that it is not always associated with pathology. For instance, autoimmune reactions are highly useful in clearing off the excess, unwanted or aged tissues from the body. Also, generation of autoimmunity occurs after the exposure to the non-self antigen that is structurally similar to the self, aided by the stimulatory molecules like the cytokines. Thus, a narrow margin differentiates immunity from auto-immunity as already discussed. Hence, finding answers for how the physiologic immunity turns to pathologic autoimmunity always remains a question of intense interest. However, this margin could be cut down only if the physiology of the immune system is better understood. The individual chapters included in this book will cover all the possible aspects of immunology and pathologies associated with it. The authors have taken strenuous effort in elaborating the concepts that are lucid and will be of reader's interest. BT - Recent Advances in Immunology to Target Cancer, Inflammation and Infections SP - Ch. 4 UR - https://doi.org/10.5772/37792 DO - 10.5772/37792 SN - PB - IntechOpen CY - Rijeka Y2 - 2022-01-16 ER -