TY - CHAP A1 - Irena Mlinaric-Rascan A2 - Miha Milek A3 - Alenka Smid A4 - Natasa Karas Kuzelicki ED1 - Despina Sanoudou Y1 - 2012-03-21 PY - 2012 T1 - S-Adenosylmethionine: A Novel Factor in the Individualization of Thiopurine Therapy N2 - The rapidly evolving field of Pharmacogenetics aims at identifying the genetic factors implicated in the inter-individual variation of drug response. These factors could enable patient sub-classification based on their treatment needs thus expediting drug development and promoting personalized, safer and more effective treatments. This book presents Pharmacogenetic examples from a broad spectrum of different drugs, for different diseases, which are representative of different stages of evaluation or application. It has been designed so as to serve both the unfamiliar reader through explanations of basic Pharmacogenetic concepts, the clinician with presentation of the latest developments and international guidelines, and the research scientist with examples of Pharmacogenetic applications, discussions on the limitations and an outlook on the new scientific trends in this field. BT - Clinical Applications of Pharmacogenetics SP - Ch. 5 UR - https://doi.org/10.5772/27070 DO - 10.5772/27070 SN - PB - IntechOpen CY - Rijeka Y2 - 2020-09-23 ER -