TY - CHAP A1 - Angela Messmer-Blust A2 - Jian Li ED1 - Angelo Squeri Y1 - 2012-03-16 PY - 2012 T1 - Hypoxia-Regulated Pro- and Anti-Angiogenesis in the Heart N2 - Coronary Artery disease is one of the leading causes of death in industrialized countries and is responsible for one out of every six deaths in the United States. Remarkably, coronary artery disease is also largely preventable. The biggest challenge in the next years is to reduce the incidence of coronary artery disease worldwide. A complete knowledge of the mechanisms responsible for the development of ischaemic heart disease is an essential prerequisite to a better management of this pathology improving prevention and therapy. This book has been written with the intention of providing new concepts about coronary artery disease pathogenesis that may link various aspects of the disease, going beyond the traditional risk factors. BT - Coronary Artery Disease SP - Ch. 5 UR - https://doi.org/10.5772/32065 DO - 10.5772/32065 SN - PB - IntechOpen CY - Rijeka Y2 - 2020-09-27 ER -