TY - CHAP A1 - Naohiro Iwata A2 - Mari Okazaki A3 - Rika Nakano A4 - Chisato Kasahara A5 - Shinya Kamiuchi A6 - Fumiko Suzuki A7 - Hiroshi Iizuka A8 - Hirokazu Matsuzaki A9 - Yasuhide Hibino ED1 - Maurizio Balestrino Y1 - 2012-03-16 PY - 2012 T1 - Diabetes-Mediated Exacerbation of Neuronal Damage and Inflammation After Cerebral Ischemia in Rat: Protective Effects of Water-Soluble Extract from Culture Medium of Ganoderma lucidum Mycelia N2 - This book reports innovations in the preclinical study of stroke, including - novel tools and findings in animal models of stroke, - novel biochemical mechanisms through which ischemic damage may be both generated and limited, - novel pathways to neuroprotection. Although hypothermia has been so far the sole "neuroprotection" treatment that has survived the translation from preclinical to clinical studies, progress in both preclinical studies and in the design of clinical trials will hopefully provide more and better treatments for ischemic stroke. This book aims at providing the preclinical scientist with innovative knowledge and tools to investigate novel mechanisms of, and treatments for, ischemic brain damage. BT - Advances in the Preclinical Study of Ischemic Stroke SP - Ch. 11 UR - https://doi.org/10.5772/32933 DO - 10.5772/32933 SN - PB - IntechOpen CY - Rijeka Y2 - 2020-08-08 ER -