TY - CHAP A1 - Andriyan Grinev A2 - Zhong Lu A3 - Vladimir Chizhikov A4 - Maria Rios ED1 - Maria Laura Garcia ED2 - Victor Romanowski Y1 - 2012-02-24 PY - 2012 T1 - Application of a Microarray-Based Assay for the Study of Genetic Diversity of West Nile Virus N2 - Viruses are small infectious agents that can replicate only inside the living cells of susceptible organisms. The understanding of the molecular events underlying the infectious process has been of central interest to improve strategies aimed at combating viral diseases of medical, veterinary and agricultural importance. Some of the viruses cause dreadful diseases, while others are also of interest as tools for gene transduction and expression and in non-poluting insect pest management strategies. The contributions in this book provide the reader with a perspective on the wide spectrum of virus-host systems. They are organized in sections based on the major topics covered: viral genomes organization, regulation of replication and gene expression, genome diversity and evolution, virus-host interactions, including clinically relevant features. The chapters also cover a wide range of technical approaches, including high throughput methods to assess genome variation or stability. This book should appeal to all those interested in fundamental and applied aspects of virology. BT - Viral Genomes SP - Ch. 8 UR - https://doi.org/10.5772/28681 DO - 10.5772/28681 SN - PB - IntechOpen CY - Rijeka Y2 - 2019-11-18 ER -