TY - CHAP A1 - Hiromichi Yonekawa A2 - Toyoyuki Takada A3 - Hiroshi Shitara A4 - Choji Taya A5 - Yoshibumi Matsushima A6 - Kunie Matsuoka A7 - Yoshiaki Kikkawa ED1 - Jorge Esparza-Gordillo ED2 - Itaru Dekio Y1 - 2012-02-22 PY - 2012 T1 - Mouse Models for Atopic Dermatitis Developed in Japan N2 - Atopic Dermatitis is a common disease characterized by inflamed, itching and dry skin. This relapsing allergic disorder has complex etiology and shows a remarkably high clinical heterogeneity which complicates the diagnosis and clinical management. This book is divided into 4 sections. The first section (Disease Etiology) describes some of the physiological mechanisms underlying Atopic Dermatitis, including alterations in the immune system and the skin-barrier function. The important role of host-microorganism interactions on the pathophysiology of Atopic Dermatitis is discussed in the second section (Microorganisms in Atopic Dermatitis). An overview of the clinical diagnostic criteria and the disease management protocols commonly used is given in the third section (Diagnosis and Clinical Management). The last section (New Treatments) describes new therapeutic approaches that are not widely used but are currently being studied due to preliminary evidence showing a clinical benefit for Atopic Dermatitis. BT - Atopic Dermatitis SP - Ch. 2 UR - https://doi.org/10.5772/26084 DO - 10.5772/26084 SN - PB - IntechOpen CY - Rijeka Y2 - 2020-01-17 ER -