TY - CHAP A1 - Toru Sugiyama ED1 - Samir A. Farghaly Y1 - 2012-02-15 PY - 2012 T1 - Second-Line Chemotherapy for Platinum- and Taxane-Resistant Epithelial Ovarian Cancer: Pegylated Liposomal Doxorubicin (PLD), Irinotecan, and Combination Therapies at Lower Doses N2 - Worldwide, Ovarian carcinoma continues to be responsible for more deaths than all other gynecologic malignancies combined. International leaders in the field address the critical biologic and basic science issues relevant to the disease. The book details the molecular biological aspects of ovarian cancer. It provides molecular biology techniques of understanding this cancer. The techniques are designed to determine tumor genetics, expression, and protein function, and to elucidate the genetic mechanisms by which gene and immunotherapies may be perfected. It provides an analysis of current research into aspects of malignant transformation, growth control, and metastasis. A comprehensive spectrum of topics is covered providing up to date information on scientific discoveries and management considerations. BT - Ovarian Cancer SP - Ch. 14 UR - https://doi.org/10.5772/28554 DO - 10.5772/28554 SN - PB - IntechOpen CY - Rijeka Y2 - 2021-09-22 ER -