TY - CHAP A1 - Michelle Sowden A2 - Baiba Grube A3 - Brigid Killilea A4 - Donald Lannin ED1 - Oliver F. Bathe Y1 - 2012-02-01 PY - 2012 T1 - Surgical Intervention Following Neoadjuvant Chemotherapy in Breast Cancer N2 - The most significant advances in cancer therapy in recent years have involved the development of systemic therapeutics. With improvements in response rates in solid tumors, opportunities have arisen to enhance the effectiveness of surgery. Administration of systemic therapy prior to surgery - neoadjuvant chemotherapy - represents one approach by which clinicians have successfully reduced the extent of surgery and, in some instances, positively impacted on clinical outcomes. This collection of works by expert clinicians from a variety of disciplines represents an exploration of the current knowledge of the role of neoadjuvant chemotherapy in diverse tumor types. BT - Neoadjuvant Chemotherapy SP - Ch. 3 UR - https://doi.org/10.5772/24519 DO - 10.5772/24519 SN - PB - IntechOpen CY - Rijeka Y2 - 2021-09-19 ER -