TY - CHAP A1 - Vassilis Zannis A2 - Andreas Kateifides A3 - Panagiotis Fotakis A4 - Eleni Zanni A5 - Dimitris Kardassis ED1 - Roya Kelishadi Y1 - 2012-02-03 PY - 2012 T1 - Pleiotropic Functions of HDL Lead to Protection from Atherosclerosis and Other Diseases N2 - Dyslipidemia has a complex pathophysiology consisting of various genetic, lifestyle, and environmental factors. It has many adverse health impacts, notably in the development of chronic non-communicable diseases. Significant ethnic differences exist due to the prevalence and types of lipid disorders. While elevated serum total- and LDL-cholesterol are the main concern in Western populations, in other countries hypertriglyceridemia and low HDL-cholesterol are more prevalent. The latter types of lipid disorders are considered as components of the metabolic syndrome. The escalating trend of obesity, as well as changes in lifestyle and environmental factors will make dyslipidemia a global medical and public health threat, not only for adults but for the pediatric age group as well. Several experimental and clinical studies are still being conducted regarding the underlying mechanisms and treatment of dyslipidemia. The current book is providing a general overview of dyslipidemia from diverse aspects of pathophysiology, ethnic differences, prevention, health hazards, and treatment. BT - Dyslipidemia SP - Ch. 9 UR - https://doi.org/10.5772/30054 DO - 10.5772/30054 SN - PB - IntechOpen CY - Rijeka Y2 - 2021-09-20 ER -