TY - CHAP A1 - Hiroshi Koriyama A2 - Hironori Nakagami A3 - Tomohiro Katsuya A4 - Ryuichi Morishita ED1 - Roya Kelishadi Y1 - 2012-02-03 PY - 2012 T1 - Functions of OSBP/ORP Family Proteins and Their Relation to Dyslipidemia N2 - Dyslipidemia has a complex pathophysiology consisting of various genetic, lifestyle, and environmental factors. It has many adverse health impacts, notably in the development of chronic non-communicable diseases. Significant ethnic differences exist due to the prevalence and types of lipid disorders. While elevated serum total- and LDL-cholesterol are the main concern in Western populations, in other countries hypertriglyceridemia and low HDL-cholesterol are more prevalent. The latter types of lipid disorders are considered as components of the metabolic syndrome. The escalating trend of obesity, as well as changes in lifestyle and environmental factors will make dyslipidemia a global medical and public health threat, not only for adults but for the pediatric age group as well. Several experimental and clinical studies are still being conducted regarding the underlying mechanisms and treatment of dyslipidemia. The current book is providing a general overview of dyslipidemia from diverse aspects of pathophysiology, ethnic differences, prevention, health hazards, and treatment. BT - Dyslipidemia SP - Ch. 7 UR - https://doi.org/10.5772/29779 DO - 10.5772/29779 SN - PB - IntechOpen CY - Rijeka Y2 - 2020-08-10 ER -