TY - CHAP A1 - Ludwika Jakubowska-Burek A2 - Elzbieta Kaczmarek A3 - Justyna Hoppe-Golebiewska A4 - Marta Kaczmarek-Rys A5 - Szymon Hryhorowicz A6 - Marcin A. Kucharski A7 - Ryszard Slomski A8 - Krzysztof Linke A9 - Agnieszka Dobrowolska-Zachwieja ED1 - Sami Karoui Y1 - 2012-01-13 PY - 2012 T1 - Genotyping of CARD15/NOD2, ATG16L1 and IL23R Genes in Polish Crohn’s Disease (CD) Patients – Are They Related to the Localization of the Disease and Extra-Intestinal Symptoms? N2 - In this book, several important points regarding Crohn's disease are discussed. In the first section, we focus on etiopathogeny of Crohn's disease and the recent advances in our overall understanding of the disease - specifically, the role of the gut epithelium, alterations of the epithelial crypts, and the roles of the different cytokines in the pathophysiology of Crohn's disease. In the second section, a diagnosis of Crohn's disease is discussed. Another particular area of focus is in the diagnosis of intestinal tuberculosis, and the role of mycobacterium avium in Crohn's disease. In the third and final section, the management of Crohn's disease is discussed, with a focus on recent evidence-based medicine recommendations. BT - Crohn's Disease SP - Ch. 3 UR - https://doi.org/10.5772/29880 DO - 10.5772/29880 SN - PB - IntechOpen CY - Rijeka Y2 - 2021-10-27 ER -