TY - CHAP A1 - Yukinori Nagakura A2 - Hiroyuki Ito A3 - Yasuaki Shimizu ED1 - William S. Wilke Y1 - 2012-01-05 PY - 2012 T1 - Animal Models of Fibromyalgia N2 - Given the potential problems that can obscure any scientific enterprise, inconsistent results across studies are bound to occur. How are we to decide what is true? Let's turn to philosophy for a reasonable answer. The mathematician-philosopher Bertrand Russell approached a similar problem in his monograph The Problems of Philosophy (Russell B, 1912). He addressed the following question: How do we know that anything is "real"? Is the only reality subjective and simply in our minds, as Bishop Berkley challenged, or can we mostly believe the objective reality? His pragmatic answer: All possibilities may be true, but when the preponderance of evidence indicates that objective reality and knowledge are the most probable case, go with it. If the preponderance of all evidence about the clinical description of fibromyalgia and it's pathogenic mechanisms and treatment strategies indicate a highly probable interrelated hypothesis, go with it. The direction of the literature on the whole trumps the less likely tangents. At the same time, remember Bertrand Russell and his pragmatic answer, and keep an open mind. BT - New Insights into Fibromyalgia SP - Ch. 3 UR - https://doi.org/10.5772/28409 DO - 10.5772/28409 SN - PB - IntechOpen CY - Rijeka Y2 - 2019-12-09 ER -