TY - CHAP A1 - Adriana Ceci A2 - Mariana Catapano A3 - Cristina Manfredi A4 - Ian Wong A5 - Mine Orlu-Gul A6 - Annarita Meneguz A7 - Paola Baiardi A8 - Oscar Della Pasqua A9 - Achille Iolascon A10 - Maurizio Scarpa A11 - Antje Neubert ED1 - Chris Rundfeldt Y1 - 2011-12-07 PY - 2011 T1 - Changes in Research and Development of Medicinal Products since the Paediatric Regulation N2 - This book represents a case study based overview of many different aspects of drug development, ranging from target identification and characterization to chemical optimization for efficacy and safety, as well as bioproduction of natural products utilizing for example lichen. In the last section, special aspects of the formal drug development process are discussed. Since drug development is a highly complex multidisciplinary process, case studies are an excellent tool to obtain insight in this field. While each chapter gives specific insight and may be read as an independent source of information, the whole book represents a unique collection of different facets giving insight in the complexity of drug development. BT - Drug Development SP - Ch. 24 UR - https://doi.org/10.5772/28797 DO - 10.5772/28797 SN - PB - IntechOpen CY - Rijeka Y2 - 2019-12-15 ER -