TY - CHAP A1 - Shuji Toda A2 - Shigehisa Aoki A3 - Kazuyoshi Uchihashi A4 - Aki Matsunobu A5 - Mai Yakushiji A6 - Akifumi Ootani A7 - Eisuke Koike A8 - Nobuhisa Yonemitsu ED1 - Yohei Tanaka Y1 - 2011-11-14 PY - 2011 T1 - The Influence of the Skin Microenvironment Air-Liquid Interface on Melanoma N2 - Melanoma is considered to be one of the most aggressive forms of skin neoplasms. Despite aggressive researches towards finding treatments, no effective therapy exists to inhibit the metastatic spread of malignant melanoma. The 5-year survival rate of metastatic melanoma is still significantly low, and there has been an earnest need to develop more effective therapies with greater anti-melanoma activity. Through the accomplishment of over 100 distinguished and respected researchers from 19 different countries, this book covers a wide range of aspects from various standpoints and issues related to melanoma. These include the biology of melanoma, pigmentations, pathways, receptors and diagnosis, and the latest treatments and therapies to make potential new therapies. Not only will this be beneficial for readers, but it will also contribute to scientists making further breakthroughs in melanoma research. BT - Breakthroughs in Melanoma Research SP - Ch. 9 UR - https://doi.org/10.5772/19104 DO - 10.5772/19104 SN - PB - IntechOpen CY - Rijeka Y2 - 2022-05-19 ER -