TY - CHAP A1 - Mario Alberghina A2 - Carla Motta A3 - Gabriella Lupo A4 - Carmelina D. Anfuso A5 - Renato Bernardini ED1 - Yohei Tanaka Y1 - 2011-11-14 PY - 2011 T1 - Melanoma-Induced Endothelial Cell Growth Involves Phospholipase A2 and COX2 Upregulation N2 - Melanoma is considered to be one of the most aggressive forms of skin neoplasms. Despite aggressive researches towards finding treatments, no effective therapy exists to inhibit the metastatic spread of malignant melanoma. The 5-year survival rate of metastatic melanoma is still significantly low, and there has been an earnest need to develop more effective therapies with greater anti-melanoma activity. Through the accomplishment of over 100 distinguished and respected researchers from 19 different countries, this book covers a wide range of aspects from various standpoints and issues related to melanoma. These include the biology of melanoma, pigmentations, pathways, receptors and diagnosis, and the latest treatments and therapies to make potential new therapies. Not only will this be beneficial for readers, but it will also contribute to scientists making further breakthroughs in melanoma research. BT - Breakthroughs in Melanoma Research SP - Ch. 7 UR - https://doi.org/10.5772/21273 DO - 10.5772/21273 SN - PB - IntechOpen CY - Rijeka Y2 - 2020-08-06 ER -