TY - CHAP A1 - Faria Zafar A2 - Takuro Nakagawa ED1 - Jelena Kušić-Tišma Y1 - 2011-09-26 PY - 2011 T1 - Regulation of Minichromosome Maintenance (MCM) Helicase in Response to Replication Stress N2 - DNA replication, the process of copying one double stranded DNA molecule to produce two identical copies, is at the heart of cell proliferation. This book highlights new insights into the replication process in eukaryotes, from the assembly of pre-replication complex and features of DNA replication origins, through polymerization mechanisms, to propagation of epigenetic states. It also covers cell cycle control of replication initiation and includes the latest on mechanisms of replication in prokaryotes. The association between genome replication and transcription is also addressed. We hope that readers will find this book interesting, helpful and inspiring. BT - Fundamental Aspects of DNA Replication SP - Ch. 5 UR - https://doi.org/10.5772/19284 DO - 10.5772/19284 SN - PB - IntechOpen CY - Rijeka Y2 - 2019-09-18 ER -