TY - CHAP A1 - Dianne C. Daniel A2 - Edward M. Johnson ED1 - Jelena Kušić-Tišma Y1 - 2011-09-26 PY - 2011 T1 - Addressing the Enigma of MCM8 in DNA Replication N2 - DNA replication, the process of copying one double stranded DNA molecule to produce two identical copies, is at the heart of cell proliferation. This book highlights new insights into the replication process in eukaryotes, from the assembly of pre-replication complex and features of DNA replication origins, through polymerization mechanisms, to propagation of epigenetic states. It also covers cell cycle control of replication initiation and includes the latest on mechanisms of replication in prokaryotes. The association between genome replication and transcription is also addressed. We hope that readers will find this book interesting, helpful and inspiring. BT - Fundamental Aspects of DNA Replication SP - Ch. 3 UR - https://doi.org/10.5772/21177 DO - 10.5772/21177 SN - PB - IntechOpen CY - Rijeka Y2 - 2020-09-18 ER -