TY - CHAP A1 - Shinichiro Nakamura A2 - Mitsuharu Ueda A3 - Naohide Ageyama A4 - Yukio Ando A5 - Ryuzo Torii ED1 - Svetlana Sarantseva Y1 - 2011-09-22 PY - 2011 T1 - Transthyretin Amyloidosis in Aged Vervet Monkeys, as a Candidate for the Spontaneous Animal Model of Senile Systemic Amyloidosis N2 - Amyloidoses are a heterogeneous group of diverse etiology diseases. They are characterized by an endogenous production of abnormal proteins called amyloid proteins, which are not hydrosoluble, form depots in various organs and tissue of animals and humans and cause dysfunctions. Despite many decades of research, the origin of the pathogenesis and the molecular determinants involved in amyloid diseases has remained elusive. At present, there is not an effective treatment to prevent protein misfolding in these amyloid diseases. The aim of this book is to present an overview of different aspects of amyloidoses from basic mechanisms and diagnosis to latest advancements in treatment. BT - Amyloidosis SP - Ch. 10 UR - https://doi.org/10.5772/19111 DO - 10.5772/19111 SN - PB - IntechOpen CY - Rijeka Y2 - 2021-10-26 ER -