TY - CHAP A1 - Daria Maria Monti A2 - Renata Piccoli A3 - Angela Arciello ED1 - Svetlana Sarantseva Y1 - 2011-09-22 PY - 2011 T1 - Apolipoprotein A-I Associated Amyloidoses: The Intriguing Case of a Natively Unfolded Protein Fragment N2 - Amyloidoses are a heterogeneous group of diverse etiology diseases. They are characterized by an endogenous production of abnormal proteins called amyloid proteins, which are not hydrosoluble, form depots in various organs and tissue of animals and humans and cause dysfunctions. Despite many decades of research, the origin of the pathogenesis and the molecular determinants involved in amyloid diseases has remained elusive. At present, there is not an effective treatment to prevent protein misfolding in these amyloid diseases. The aim of this book is to present an overview of different aspects of amyloidoses from basic mechanisms and diagnosis to latest advancements in treatment. BT - Amyloidosis SP - Ch. 4 UR - https://doi.org/10.5772/20127 DO - 10.5772/20127 SN - PB - IntechOpen CY - Rijeka Y2 - 2021-07-30 ER -