TY - CHAP A1 - Tomoyuki Takano ED1 - Željka Petelin Gadže Y1 - 2011-09-15 PY - 2011 T1 - Polymicrogyria: A Clinical and Experimental Approach to Epilepsy N2 - Epilepsy is a neurological condition that accompanies mankind probably since its inception. About 400 years before Christ, the disease was already known by Hippocrates, who wrote the book "On The Sacred Disease". Classically, epilepsy has been defined as a chronic condition characterized by an enduring propensity to generate seizures, which are paroxysmal occurring episodes of abnormal excessive or synchronous neuronal activity in the brain. Out of all brain disorders, epilepsy is the one that offers a unique opportunity to understand normal brain functions as derived from excessive dysfunction of neuronal circuits, because the symptoms of epileptic seizures are not the result of usual loss of function that accompanies many disease that affect the brain. I am therefore extremely honoured to present this book. The 15 very interesting chapters of the book cover various fields in epileptology - they encompass the etiology and pathogenesis of the disease, clinical presentation with special attention to the epileptic syndromes of childhood, principles of medical management, surgical approaches, as well as social aspects of the disease. BT - Epilepsy in Children SP - Ch. 1 UR - https://doi.org/10.5772/17342 DO - 10.5772/17342 SN - PB - IntechOpen CY - Rijeka Y2 - 2021-08-05 ER -