TY - CHAP A1 - CD Smith A2 - M Badadani A3 - A Nalbandian A4 - E Dec A5 - J Vesa A6 - S Donkervoort A7 - B Martin A8 - GD Watts A9 - V Caiozzo A10 - V Kimonis ED1 - Suzanne De La Monte Y1 - 2011-09-06 PY - 2011 T1 - Valosin-Containing Protein (VCP) Disease and Familial Alzheimer’s Disease: Contrasts and Overlaps N2 - The Clinical Spectrum of Alzheimer's Disease: The Charge Toward Comprehensive Diagnostic and Therapeutic Strategies is highly informative and current. Acknowledged experts in the field critically review both standard and under-appreciated clinical, behavioral, epidemiological, genetic, and neuroimaging attributes of Alzheimer's disease. The collection covers diverse topics of interest to clinicians and researchers alike. Experienced professionals and newcomers to the field will benefit from the read. The strengths and weaknesses of current clinical, non-invasive, neuro-imaging, and biomarker diagnostic approaches are explained. The perspectives give fresh insights into the process of neurodegeneration. Readers will be enlightened by the evidence that the neural circuits damaged by neurodegeneration are much broader than conventionally taught, suggesting that Alzheimer's could be detected at earlier stages of disease by utilizing multi-pronged diagnostic approaches. This book inspires renewed hope that more effective treatments could be developed based upon the expanding list of potential therapeutic targets. BT - The Clinical Spectrum of Alzheimer's Disease SP - Ch. 16 UR - https://doi.org/10.5772/18811 DO - 10.5772/18811 SN - PB - IntechOpen CY - Rijeka Y2 - 2020-11-23 ER -