TY - CHAP A1 - Thomas G. Koch A2 - Lorenzo Moroni A3 - Younes Leysi-Derilou A4 - Lise C. Berg ED1 - Daniel Eberli Y1 - 2011-08-17 PY - 2011 T1 - Joint Cartilage Tissue Engineering and Pre-Clinical Safety and Efficacy Testing N2 - Tissue Engineering may offer new treatment alternatives for organ replacement or repair deteriorated organs. Among the clinical applications of Tissue Engineering are the production of artificial skin for burn patients, tissue engineered trachea, cartilage for knee-replacement procedures, urinary bladder replacement, urethra substitutes and cellular therapies for the treatment of urinary incontinence. The Tissue Engineering approach has major advantages over traditional organ transplantation and circumvents the problem of organ shortage. Tissues reconstructed from readily available biopsy material induce only minimal or no immunogenicity when reimplanted in the patient. This book is aimed at anyone interested in the application of Tissue Engineering in different organ systems. It offers insights into a wide variety of strategies applying the principles of Tissue Engineering to tissue and organ regeneration. BT - Tissue Engineering for Tissue and Organ Regeneration SP - Ch. 10 UR - https://doi.org/10.5772/24096 DO - 10.5772/24096 SN - PB - IntechOpen CY - Rijeka Y2 - 2021-10-27 ER -