TY - CHAP A1 - Jaime A. Pineda A2 - Heather Pelton A3 - Oriana Aragon A4 - Jia-Min Bai A5 - Matt Erhart A6 - Dane Chambers A7 - Burcu Darst A8 - Ernesto Enrique A9 - Steven Gilmore A10 - Stephen Johnson A11 - Albert Anaya A12 - Alicia Trigeiro A13 - Dan T. Lotz A14 - Nicholas Pojman A15 - Tom Gamage A16 - David Linderman ED1 - Valsamma Eapen Y1 - 2011-08-17 PY - 2011 T1 - Behavioral and Electrophysiological Characterization of Induced Neural Plasticity in the Autistic Brain N2 - The book covers some of the key research developments in autism and brings together the current state of evidence on the neurobiologic understanding of this intriguing disorder. The pathogenetic mechanisms are explored by contributors from diverse perspectives including genetics, neuroimaging, neuroanatomy, neurophysiology, neurochemistry, neuroimmunology, neuroendocrinology, functional organization of the brain and clinical applications from the role of diet to vaccines. It is hoped that understanding these interconnected neurobiological systems, the programming of which is genetically modulated during neurodevelopment and mediated through a range of neuropeptides and interacting neurotransmitter systems, would no doubt assist in developing interventions that accommodate the way the brains of individuals with autism function. In keeping with the multimodal and diverse origins of the disorder, a wide range of topics is covered and these include genetic underpinnings and environmental modulation leading to epigenetic changes in the aetiology; neural substrates, potential biomarkers and endophenotypes that underlie clinical characteristics; as well as neurochemical pathways and pathophysiological mechanisms that pave the way for therapeutic interventions. BT - Autism SP - Ch. 23 UR - https://doi.org/10.5772/18484 DO - 10.5772/18484 SN - PB - IntechOpen CY - Rijeka Y2 - 2020-09-29 ER -