TY - CHAP A1 - Li-Jun Xue A2 - Quan-Sheng Su A3 - Xiao-Bei Mao A4 - Xiao-Bei Liu A5 - Qing Lin A6 - Chang Liu A7 - Yong Lin A8 - Ji-Hong Yang A9 - Hong-Ju Yu A10 - Xiao-Yuan Chu ED1 - Dr.Mahmoud Lotfy Y1 - 2011-06-15 PY - 2011 T1 - A Double-Edged Sword: Roles of Helicobacter Pylori in Gastric Carcinoma N2 - Gastric cancer is one of the most common tumors worldwide. It has a heterogeneous milieu, where the genetic background, tumor immunology, oxidative stress, and microbial infections are key players in the multiple stages of tumorigenesis. These diverse factors are linked to the prognosis of the gastric cancer and the survival of gastric cancer patients. This book is appropriate for scientists and students in the field of oncology, gastroenterology, molecular biology, immunology, cell biology, biology, biochemistry, and pathology. This authoritative text carefully explains the fundamentals, providing a general overview of the principles followed by more detailed explanations of these recent topics efficiently. The topics presented herein contain the most recent knowledge in gastric cancer concerning the oncogenic signaling, genetic instability, the epigenetic aspect, molecular features and their clinical implications, miRNAs, integrin and E-cadherin, carbohydrate-associated-transferases, free radicals, immune cell responses, mucins, Helicobacter-pylori, neoadjuvant and adjuvant therapy, prophylactic strategy for peritoneal recurrence, and hepatic metastasis. BT - Gastric Carcinoma SP - Ch. 13 UR - https://doi.org/10.5772/16691 DO - 10.5772/16691 SN - PB - IntechOpen CY - Rijeka Y2 - 2021-10-27 ER -