TY - CHAP A1 - Loyer Pascal A2 - Corlu Anne ED1 - Herve Seligmann Y1 - 2011-08-01 PY - 2011 T1 - Regulation of the G1/S Transition in Adult Liver: Expression and Activation of the Cyclin Dependent Kinase Cdk1 in Differentiated Hepatocytes is Controlled by Extracellular Signals and is Crucial for Commitment to DNA Replication N2 - The study of DNA advanced human knowledge in a way comparable to the major theories in physics, surpassed only by discoveries such as fire or the number zero. However, it also created conceptual shortcuts, beliefs and misunderstandings that obscure the natural phenomena, hindering its better understanding. The deep conviction that no human knowledge is perfect, but only perfectible, should function as a fair safeguard against scientific dogmatism and enable open discussion. With this aim, this book will offer to its readers 30 chapters on current trends in the field of DNA replication. As several contributions in this book show, the study of DNA will continue for a while to be a leading front of scientific activities. BT - DNA Replication SP - Ch. 23 UR - https://doi.org/10.5772/19631 DO - 10.5772/19631 SN - PB - IntechOpen CY - Rijeka Y2 - 2021-09-18 ER -