@incollection{Shirai13, author = {Tomohisa Ogawa and Tsuyoshi Shirai}, title = {Experimental Molecular Archeology: Reconstruction of Ancestral Mutants and Evolutionary History of Proteins as a New Approach in Protein Engineering}, booktitle = {Protein Engineering}, publisher = {IntechOpen}, address = {Rijeka}, year = {2013}, editor = {Tomohisa Ogawa}, chapter = {5}, doi = {10.5772/56255}, url = {https://doi.org/10.5772/56255} }